Trillium extracellular vesicles 2022

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Editorial
1. Extracellular vesicles – all back to normal?
  
  13.09.2022
  
  Julia Gross, Gregor Fuhrmann
  
  After almost two years of online meetings, the German Society for Extracellular Vesicles (gsev.org) was holding their autumn meeting in September 2021 in Freiburg.…
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Meet the researcher
1. A few questions to Prof. Dr. Dave Carter, Evox and Oxford Brookes
  13.09.2022
  
  How did you enter the extracellular vesicle (EV) research field?
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Research articles
1. Proteomic profiling of extracellular vesicles suggests Collectin10 as potential biomarker in relapsing head and neck squamous cell carcinoma
  
  13.09.2022
  
  Dapi Menglin Chiang (corresponding author), Laura Benecke, Chen Meng, Christina Ludwig, Laurent Muller (shared last author), Michael W. Pfaffl (shared last author)
  
  IntroductionHead and neck squamous cell carcinoma (HNSCC) is the 6th most common cancer worldwide [1]. Most HNSCC patients present at a locally advanced stage, and…
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2. Characterization of two novel neutral sphingomyelinase 2 inhibitors in endosomal sorting and extracellular vesicle biogenesis
  
  13.09.2022
  
  Dolma Choezom, Julia Christina Gross (corresponding author)
  
  IntroductionSphingomyelinase or sphingomyelindiesterase (SMPD), a member of the DNase-I superfamily of enzymes, hydrolyzes the phosphodiester bond of the…
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Method contribution
1. An optimized protocol for the enrichment of small vesicles from murine and non-human primate heart tissue
  
  13.09.2022
  
  Federico Bleckwedel (The authors contributed equally), Giulia Germena (The authors contributed equally), Rabea Hinkel, Laura C. Zelarayán (Corresponding Author)
  
  IntroductionEVs are a heterogeneous group of bilayer membrane nanoparticles that play roles in diverse intercellular communication in short and long-range…
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Minireviews
1. Mast cell-tumor cell interactions via extracellular vesicles
  
  13.09.2022
  
  Phillipp Brockmeyer (Corresponding author), Bernhard Hemmerlein
  
  Mast cells in health and diseaseMCs, first described in 1878, are an important part of the immune system [1]. They arise from pluripotent bone marrow progenitor…
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2. Synovial fluid-derived extracellular vesicles - potential biomarkers of osteoarthritis
  
  13.09.2022
  
  Marko Morávek, Ján Rosocha, Tímea Špaková
  
  IntroductionOsteoarthritis (OA) of the joint is one of the most common diseases of the musculoskeletal system. It is accompanied by various types of manifestations…
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EVs in Parkinson’s
1. Extracellular vesicles – upcoming biomarkers in Parkinson's disease's biofluids
  
  13.09.2022
  
  Alexander Weiß, Andreu Matamoros-Angles, Fanni Annamária Boros, Philipp Arnold, Friederike Zunke
  
  Parkinson's DiseaseParkinson´s disease (PD), the second most common neurodegenerative disease, is characterized by progressive degeneration of dopaminergic neurons…
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EVs and cilia
13.09.2022

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Technical note
1. Extracellular vesicles (EVs): you know they are important, so make sure you can detect them!
  
  10.10.2022
  
  All cells, healthy or otherwise, release EVs as key mediators of intercellular communication. EVs are membrane derived structures that include exosomes,…
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2. NTA goes co-localization: Characterization of double-labelled extracellular vesicles
  
  10.10.2022
  
  Sascha Raschke, Henry Dehne, Lorenz Hailer, Clemens Helmbrecht
  
  Introduction Techniques incorporating fluorescence as detection principle can be regarded as the analytical backbone in almost every bioanalytical laboratory. For…
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