Literatur

[1] Mandel P, Metais P. Les acides nucléiques du plasma sanguin chez l‘homme. Comptes rendus des seances de la Societe de biologie et de ses filiales, 1948; 142: 241–3

[2] Tan E et al. Deoxybonucleic acid (DNA) and antibodies to DNA in the serum of patients with systemic lupus erythematosus. J Clin Invest, 1966; 45: 1732–40

[3] Ehlert T et al. Establishing PNB-qPCR for quantifying minimal ctDNA concentrations during tumour resection. Scientific Reports 2017; 7: 8876

[4] Beiter T et al. Short-term treadmill running as a model for studying cell-free DNA kinetics in vivo. Clin Chem 2011; 57: 633–6

[5] Frühbeis C et al. Physical exercise induces rapid release of small extracellular vesicles into the circulation. Journal of extracellular vesicles 2015; 4.1: 28239

[6] Helmig S et al. Release of bulk cell free DNA during physical exercise occurs independent of extracellular vesicles. Eur J appl Physiol 2015; 115 : 2271–80

[7] Balaj L et al. Tumour microvesicles contain retrotransposon elements and amplified oncogene sequences. Nat Commun 2011, doi: 10.1038/ncomms1180

[8] Thakur BK et al. Double-stranded DNA in exosomes: a novel biomarker in cancer detection. Cell Res 2014; 24: 766

[9] Mouliere F, Rosenfeld N. Circulating tumor-derived DNA is shorter than somatic DNA in plasma. Proceedings of the National Academy of Sciences 2015; 112.11: 3178–9