Extracellular vesicle-derived microRNA biomarkers: goals and pitfalls

Liquid biopsy-derived extracellular vesicles (EVs) are an auspicious source for transcriptomic biomarker studies. Here, we review the potential of EV microRNAs (miRNAs) biomarkers, exemplary outline commonly used methods to elucidate new biomarker signatures, and pivotally discuss their applicability at present.

Keywords: extracellular vesicles, liquid biopsies, transcriptomic biomarkers, microRNAs

https://doi.org/10.47184/tev.2020.01.04

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Authors
Stefanie Hermann Correspondence
Christian Grätz
Benedikt Kirchner
Michael W. Pfaffl
School of Life Sciences, 85354 Freising-Weihenstephan, Germany
Animal Physiology & Immunology,
Technical University of Munich,