The Magnis system provides a complete system for NGS library preparation that is fully automated and delivers reproducible results, making it easy to assay multiple genes and complex genetic aberrations from genomic DNA including degraded samples such as formalin-fixed paraffin-embedded (FFPE).

This new bench-top instrument self-detects and tunes; the reagents come pre-aliquoted; and pre-set protocols are included.

The system requires minimal expertise to run. The onboard wizard allows assays to be set up in under five minutes. In addition, the Magnis notifies users of correct reagent placement through automated barcode checking. Upon pressing the start button, the user can walk away from the instrument, yet visually check progress through the wizard and the LED status indicator.

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The Agilent SureSelect Human All Exon V8 features a slim and efficient design, powered by machine learning-based probe selection and placement.

The panel provides comprehensive and updated coverage of human protein-coding regions from major public databases, such as RefSeq, CCDS, and GENCODE. It also covers the TERT promoter and hard-to-capture exons that are omitted by other exome sequencing panels on the market.
 

Most importantly, the panel delivers excellent enrichment performance and sequencing economy, making it ideal for routine exome sequencing.
 

The SureSelect Human AIl Exon V8 exome panel is fully customizable. For applications that require augmentation or enhancement of the exome, Agilent provides a suite of predesigned content that can be leveraged and combined with the core exome content offered by SureSelect Human All Exon V8 to quickly create a customized exome panel. Examples of predesigned content include designs such as untranslated regions (UTRs), non-coding clinical variants (NCVs), copy number variations (CNVs) backbone, pan-cancer biomarkers, and the mitochondrial genome.
 

The SureSelect Human All Exon V8 exome enrichment workflow is natively supported on the Agilent Bravo Automated Liquid Handling platform for high-throughput sample preparation and the Agilent Magnis NGS Prep system for complete, walkaway automation.

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Keep your library prep workflows simple
 

The SureSelect XT HS2 RNA Reagent kit gives you a rapid, streamlined workflow for the parallel, targeted RNA and DNA-seq from low-input and/or degraded samples. Now you can efficiently profile your gene expression and fusion analyses and reap the benefits of:

• Fast turnaround time – complete your workflow in only 1-2 days
• Optimized for FFPE – get strand-specific RNA libraries from 10 to 200 ng of FFPE RNA
• More reliable results – Molecular barcodes let you measure gene expression accurately
• An integrated workflow – the parallel RNA/DNA workflow makes for seamless lab integration

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Agilent community designs are NGS panels and microarrays created by our customers and deployed successfully in their laboratories. As many of these designs have potential to be used more widely, we are now making them available to you as made-to-order products, manufactured to Agilent quality in our production facility.
 

Not only will our community designs program save you time designing target enrichment probe libraries and arrays, but it will also give you access to the experience and expertise of our established customer base. These expert-validated designs have been tested in their labs for unique applications and will now be available to all Agilent customers. The designs are ready to order with a click of a button.
 

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